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Cervical and Endometrial Cancer Screening in Patients Seeking Gender-Affirming Hysterectomy

RecruitingObservational study

Who can join

Ages 18 and older · All sexes

Full eligibility criteria
Inclusion Criteria:

* 18 years and older
* Able to provide voluntary written consent prior to the performance of any research related activity. Patients who can provide informed consent
* Able to understand, speak, read, and write in English
* Patients who have undergone hysterectomy, or plan to have a hysterectomy
* Patients who are transgender and gender diverse"

Exclusion Criteria:

* Opted out of research
* \<18 years old
* Lacks capacity to consent/has diminished capacity to consent
* Cannot provide informed consent
* Those on the study's community advisory board

About the study

This study aims to quantify the rates of cervical cancer screening and endometrial sampling prior to gender-affirming hysterectomy, assess the need for these tests in TGD individuals, and explore patient-centered options for these tests. By assessing the status of testing and correlation with hysterectomy pathology, this study will provide preliminary data on the current state of guideline-concordant care and provide initial evidence for the development of evidence-based guidelines in the future

What is being tested

Sponsor: University of Minnesota · Participants: 40 · Started: Jun 30, 2025

Contact the study team

Official record on ClinicalTrials.gov — NCT07075731

Locations in the U.S.

MinnesotaUniversity of Minnesota, Minneota

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.