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Virtual Art Therapy Assisted Re-Integration to Improve Biopsychosocial Outcomes in Adolescent and Young Adult Cancer Survivors, AVATARS Trial

Recruiting

AVATARS: Adolescent and Young Adult Virtual Art Therapy Assisted Re-Integration During Cancer Survivorship

Who can join

Ages 10 to 25 · All sexes

Full eligibility criteria
Inclusion Criteria:

* If young adult- aged 18-25 years of age at the time of enrollment and able to provide informed consent, if adolescent- aged 10-17 years at the time of enrollment and able to provide
* Mild or greater depression \[Patient Health Questionnaire (PHQ-A) score \> 5\]
* Received a cancer diagnosis during the past year, or completed cancer treatment within the past five years (extended survivorship)
* Have access to an electronic device which supports virtual videoconferencing (e.g., personal device or public library access)
* Able to read and write in English

Exclusion Criteria:

* Visual or cognitive impairment which may impede completing the art project or the data collection measures
* Endorsed suicidality (via PHQ-A or otherwise)

About the study

This clinical trial tests the feasibility, usability and acceptability of a virtual art therapy assisted re-integration (AVATARS) intervention to improve biopsychosocial outcomes, such as anxiety, depression, resilience, emotional regulation, stress, and cognition, among adolescent and young adult (AYA) cancer survivors. AYA cancer survivors (especially those treated at adult cancer centers) historically experience worse psychosocial outcomes and lack age appropriate psychosocial support compared to older adult cancer survivors. Creative art therapy accesses the limbic system to provide a corrective emotional experience in response to trauma and can help patients visually express depression, anxiety, and existential fears, process traumatic events, and regain agency and control. The AVATARS intervention may be a feasible, useable and acceptable way to improve biopsychosocial outcomes among AYA cancer survivors.

What is being tested

Sponsor: Mayo Clinic · Participants: 30 · Started: Jul 2, 2025

Contact the study team

Official record on ClinicalTrials.gov — NCT07089927

Locations in the U.S.

ArizonaMayo Clinic in Arizona, Scottsdale
MinnesotaMayo Clinic in Rochester, Rochester (Not yet recruiting)

From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.