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A Study Of CS Reducer For Symptomatic Heart Failure With HFpEF And CMD

CMR Substudy of Coronary Sinus Reducer for the Management of Symptomatic Heart Failure With a Preserved Ejection Fraction (HFpEF) Associated With Coronary Microvascular Dysfunction (CMD)

Who can join

Ages 18 and older · All sexes

Inclusion Criteria:

* Age ≥18
* Enrollment in main CS-reducer HFPEF study IRB# 25-002292

Exclusion Criteria:

* Metal implants that are not suitable for MRI
* Inability or unwillingness of individual to give written informed consent.

About the study

To evaluate the effect of CS reducer implantation in patients with HFPEF and CMD on myocardial ischemia, measured by stress myocardial perfusion using cardiovascular magnetic resonance (CMR)

What is being tested

• Cardiovascular Magnetic Resonance (CMR) (diagnostic test)

Sponsor: Mayo Clinic · Participants: 25 · Started: Oct 16, 2025

Contact the study team

• Diana Albers · Phone: 507-255-6884

Official record on ClinicalTrials.gov — NCT07093528

Locations in the U.S.

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.