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Development and Pilot Trial of Focused ACT (FACT) for Patients With Advanced Cancer

Recruiting

Who can join

Ages 18 and older · All sexes

Full eligibility criteria
Inclusion Criteria:

* Adult cancer patients diagnosed with advanced cancer (solid tumor and hematologic)
* Progressed past at least one line of palliative systemic cancer therapy
* Patient followed by Supportive Care Outpatient Service
* English speaking
* Able to provide written informed consent
* Willing to participate in a stress and coping program
* Willing to identify 1-2 important areas of life they might like to discuss with a counselor
* Moderate levels of death anxiety on DADDS (\>=25, on 0-75 scale)
* Access to technology to support institutionally approved video-conferencing platform of Zoom

Exclusion Criteria:

* ECOG performance status \>=3 "capable of only limited selfcare; confined to bed or chair more than 50% of waking hours"
* Currently participating in regular psychotherapy (patient defined)
* Documented out of hospital DNR (do not resuscitate) orders
* Presence of active suicidal ideation or need for a higher level of care (as determined by Supportive Care physician or licensed mental health clinician).

About the study

To learn about the effects of an intervention program called Focused Acceptance and Commitment Therapy (FACT) on the level of anxiety patients diagnosed with cancer feel about death.

To learn if an intervention program called Focused Acceptance and Commitment Therapy (FACT), designed to help reduce death-related anxiety, is effective and acceptable to patients diagnosed with advanced cancer.

What is being tested

Sponsor: M.D. Anderson Cancer Center · Participants: 70 · Started: Jul 21, 2025

Contact the study team

Official record on ClinicalTrials.gov — NCT07105033

Locations in the U.S.

TexasThe University of Texas M. D. Anderson Cancer Center, Houston

From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.