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Bromelain for Post-surgery Facial Swelling
Effectiveness of Bromelain Supplement in Reduction of Facial Swelling Caused by Orthognathic Surgery
Who can join
Ages 18 to 65 · All sexes
Full eligibility criteria
Inclusion Criteria: * undergoing orthognathic surgery Exclusion Criteria: * craniofacial anomalies * incomplete patient data * systemic disease that could affect healing * allergy to latex or pineapple * under 18 years of age * non english speaking
About the study
The goal of this clinical trial is to learn if Bromelain Supplement works to decrease the amount of swelling or the amount of time swelling is present following jaw surgery. It will also learn about the safety of Bromelain supplement. The main questions it aims to answer are:
Does Bromelain decrease facial swelling following orthognathic, or jaw, surgery? Does Bromelain supplement decrease the amount of time that patients are swollen following orthognathic, or jaw, surgery?
Participants will:
Take Bromelain supplement once daily for 9 days total. Take 2 days before surgery and 7 days following surgery.
Keep a log of when the bromelain supplement is taken as well as another other medications.
Visit the clinic with pre and post surgical protocol
What is being tested
- Bromelain (dietary supplement)
Sponsor: Mohamed Bazina · Participants: 200 · Started: Sep 8, 2025
Contact the study team
- Emma E Palmer, DMD · Phone: 859-358-6346
Official record on ClinicalTrials.gov — NCT07115212
Locations in the U.S.
| Kentucky | University of Kentucky, Lexington |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.