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Biological Drivers of Cervical Cancer and Side Effects From Radiation Therapy
Understanding the Biological Drivers of Cervical Cancer and Side Effects From Radiation Therapy
Who can join
Ages 18 and older · Women
Full eligibility criteria
Inclusion Criteria: * Age 18 years or older * Pathological diagnosis of cervical cancer * Scheduled to receive brachytherapy for cervical cancer Exclusion Criteria: * Pregnancy or lactation * Inability to provide a tissue sample
About the study
The goal of this observational study is to learn more about the biology of cervical cancer in women who receive radiation therapy for this condition. The main question it aims to answer is:
Does radiation therapy alter the expression of tissue factor and other molecules in cervical cancer over time?
Participants already scheduled for radiation therapy for cervical cancer as part of their regular medical care will provide blood and biopsies of cervical cancer or of the upper portion of the vagina before, during, and on the last day of radiation therapy.
What is being tested
- Brachytherapy (radiation)
Sponsor: University of California, San Diego · Participants: 20 · Started: Aug 4, 2025
Contact the study team
- Jyoti Mayadev, MD · Phone: 858-822-5354
- Erika Peterson · Phone: 858-822-5354
Official record on ClinicalTrials.gov — NCT07121543
Locations in the U.S.
| California | University of California San Diego, La Jolla |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.