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Mango Intake and Gut and Cardiometabolic Health in Hispanic/Latino Adolescents

RecruitingHealthy volunteers welcome

The Influence of Mango-Derived Intestinal Microbial Metabolites on Gut Permeability, Inflammation, and Cardiometabolic Health Markers in Hispanic/Latino Adolescents

Who can join

Ages 12 to 19 · All sexes · Healthy volunteers welcome

Full eligibility criteria
Inclusion Criteria:

* \- Male or Female 12-19 years old
* BMI ≥ 85th percentile (https://www.bcm.edu/bodycomplab/BMIapp/BMI-calculator-kids.html)
* Self-reported Hispanic/Latino
* Subject is willing and able to comply with the study protocols
* Subject is willing to consume the test products
* Female-specific criteria: if menstruating, eumenorrheic (regular monthly menstrual cycles of 25-30-days in length)
* Access to a smartphone or tablet at least 1x / day and willing to take pictures associated with the products to be consumed in the study

Exclusion Criteria:

* \- Reported food allergies.
* Currently taking prescription drugs, with the exception of asthma inhalers, which are allowed
* BMI \<85th percentile (https://www.bcm.edu/bodycomplab/BMIapp/BMI-calculator-kids.html)
* Current participation in a moderate or high-intensity daily exercise routine
* Self-reported disease, serious illness, or who are currently under acute medical care.
* Currently taking prescription drugs.
* Any supplement use, including multi-vitamin/ mineral, herbal, plant or botanical, fish oil, and oil supplements, and not willing to discontinue before starting the study.
* Vegetarian or vegan diet
* Self-reported malabsorption or gastrointestinal issues
* Fruit and vegetable intake exceeding daily recommendations of 5 servings
* Smoking (vaping, conventional nicotine-containing products or marijuana)
* Current enrollee in a clinical research study

About the study

Mangos contain a number of nutrients that may improve gut and metabolic health. The purpose of this research is to see how eating mangos every day for 4 weeks instead of snacks high in calories and low in nutrients such as cookies, crackers, chips, and candy can impact adolescent health.

What is being tested

Sponsor: University of California, Davis · Participants: 25 · Started: Oct 1, 2025

Contact the study team

Official record on ClinicalTrials.gov — NCT07125001

Locations in the U.S.

CaliforniaAcademic Surge; Ragle Human Nutrition Research Center, Davis

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.