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Project CARE: CAncer Risk Evaluation

Project CARE: CAncer Risk Evaluation (CARE)

Who can join

Ages 18 to 70 · All sexes · Healthy volunteers welcome

Inclusion Criteria

1. Age 18 to 70 years
2. Able to read and speak English
3. Have an email address or mobile phone number in EPIC and/or are enrolled in MyChart
4. Receiving health care in Family Medicine or General Internal Medicine at Rutgers Health within the past 2 years
5. Have not opted out of receiving research-related communications
6. Have internet access (via smartphone, tablet, or computer)

Exclusion Criteria

1. Dementia (e.g., Alzheimer's disease) as indicated in EPIC
2. Unable to access the Internet (via smartphone, tablet, or computer)
3. Previous germline genetic testing for hereditary cancer risk
4. Opted out of research participation in EPIC
5. Have a personal history of cancer

About the study

The purpose of Project CARE (cancer risk assessment and evaluation) research study is to explore the acceptance and feasibility of a study-initiated proactive outreach and digital care delivery model for conducting hereditary cancer risk assessment in primary care settings and facilitating genetic risk evaluation for patients flagged as high risk. Potential participants will be recruited from Rutgers Health primary care sites (family practice and general internal medicine). EPIC will be used to identify all potential participants and they will be invited to participate in the study. Consented participants will be provided a link via email, and or text message to engage with a Relational Agent (RA, chatbot), through the patient portal for cancer risk assessment and genetic education. Those identified as high risk will be offered genetic counseling and testing.

The research questions the study aims to answer are:

1. What percent of patients who completed the RA are identified as high risk? 2. What percent of patients who engaged with the risk assessment were identified as high risk? 3. What percent of high-risk patients had genetic counseling or genetic testing within 4 months of completing the risk assessment?

What is being tested

• Relational Agent ( RA) Alex (behavioral)

Sponsor: Anita Y. Kinney, PhD, RN · Participants: 210 · Started: Nov 19, 2025

Contact the study team

• Julie Chapman-Greene, PhD, MPH · Phone: 732-865-3375
• Emily Heidt, MPH · Phone: 732-235-8930

Official record on ClinicalTrials.gov — NCT07130487

Locations in the U.S.

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.