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Real Life Evaluation of the LibAirty Airway Clearance System in Adults With Bronchiectasis (RELACS)

Real Life Evaluation of the LibAirty Airway Clearance System in Adults With Bronchiectasis (RELACS) - A Prospective Study

Who can join

Ages 21 and older · All sexes

Inclusion Criteria:

1. Have a radiological diagnosis of Bronchiectasis based on high resolution chest CT scan
2. Have bronchiectasis characterized by either:

   * Daily productive cough (as determined by a treating physician)
   * OR Available documentation from the last 12 months of 2 or more pulmonary exacerbations requiring antibiotic therapy
3. Be at age ≥ 21 years
4. Prescribed and receives the LibAirty system for home use
5. Be on a standard of care treatment plan that includes at least one physician encounter every 6 months
6. No change in treatment for Bronchiectasis in the 2-month period prior to enrollment
7. Signed informed consent

Exclusion Criteria:

1. Inability to independently perform therapy with the LibAirty system as directed
2. Any other condition that, in the opinion of the PI, could jeopardize the safety of the subject or impact the validity of the study results.
3. Pregnancy or planned pregnancy during the expected duration of the trial (12 months).

About the study

The purpose of this study is to collect data to assess the use of the LibAirty™ System for improving bronchiectasis symptoms and healthcare resource utilization when it is used at home.

The main question this study is trying to answer is: How often do adults with bronchiectasis experience pulmonary exacerbations (flare-ups of their lung condition) while using the LibAirty™ airway clearance system at home?

Participants will use the LibAirty™ airway clearance system at home as prescribed by their doctor - the device is not being provided as part of the study. The study will last for 12 months from the time participants begin using LibAirty.

During the study period, participants will continue with their usual clinic visits. At some of these regular visits (up to 4 times over the year), participants will be asked to complete short questionnaires about their bronchiectasis symptoms and their experience using LibAirty. At these same visits, the study team will also review participants' medical records and collect information related to their bronchiectasis condition, such as test results, medications, and any hospital or emergency room visits.

What is being tested

• Airway clearance system (device)

Sponsor: Synchrony-Medical, Ltd · Participants: 200 · Started: Aug 20, 2025

Contact the study team

Official record on ClinicalTrials.gov — NCT07135284

Locations in the U.S.

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.