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Tibial Nerve Stimulation for Pediatric Spina Bifida Neurogenic Bladder

Recruiting

A Randomized Control Trial of Transcutaneous Tibial Nerve Stimulation for Neurogenic Bladder in the Pediatric Population

Who can join

Ages 4 to 17 · All sexes

Full eligibility criteria
Inclusion Criteria:

* chronic neurogenic bladder
* Spina Bifida diagnosis
* Use of overactive bladder medication(s)
* Stable bladder medications for ≥ 3 months

Exclusion Criteria:

* Progressive SCI (ex: transverse myelitis, polio, etc.)
* Other lower urinary tract pathology or surgery
* 2+ pitting edema in the legs that does not resolve
* Known peripheral neuropathy or injury to the path of the tibial nerve
* Cancer in the tibial nerve pathway and/or lower urinary tract
* Inability to elicit the motor response with electric stimulation
* Inability to complete the tTNS proficiency checklist (guardians)
* Non-English speaking (guardians)

About the study

The purpose of this study is to determine the safety, feasibility, and compliance of a daily home transcutaneous tibial nerve stimulation (tTNS) protocol in children with chronic neurogenic bladder (NB) provided by self or caregiver for 4 weeks and to estimate the efficacy of tTNS

What is being tested

Sponsor: The University of Texas Health Science Center, Houston · Participants: 20 · Started: Mar 27, 2026

Contact the study team

Official record on ClinicalTrials.gov — NCT07136688

Locations in the U.S.

TexasThe University of Texas Health Science Center and Houston, Houston

Conditions

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.