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Comparing Outcomes and Complications Following Mastisol Application for Clubfoot Casting

A Randomized Controlled Trial Comparing Outcomes and Complications Following Mastisol Application for Clubfoot Casting

Who can join

0 Weeks – 12 Weeks · All sexes

Inclusion Criteria:

* Patients with bilateral clubfeet
* Starting standard of care treatment with the Ponseti method between 0-12 weeks of age

  * For patients born pre-maturely their eligibility age will be based on a corrected gestational age
* Patients for whom at least one parent/guardian is able to converse, read, and write in English

Exclusion Criteria:

* Patients who do not have bilateral clubfoot
* Patients who are starting treatment for clubfoot after 12 weeks of age
* Patients whose parents/guardians are unable to converse, read, and write in English
* Patients whose parents/guardian do not provide or are not able to provide informed consent

About the study

The purpose of this study is to assess if the application of Mastisol, a liquid adhesive, improves outcomes during bilateral clubfoot casting and reduces complications and development of complex clubfoot for the duration of their casting and up to 5 years follow-up.

What is being tested

• Mastisol (device)

Sponsor: University of Wisconsin, Madison · Participants: 100 · Started: Feb 11, 2026

Contact the study team

• Ava Barker · Phone: (608)-263-2356

Official record on ClinicalTrials.gov — NCT07154550

Locations in the U.S.

From ClinicalTrials.gov, data retrieved Oct 2, 2026. Each study sets its own eligibility; the study team decides who can join.