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A Study to Evaluate Community-Based Measures to Increase RSV Vaccine Use Among Latino Adults

Motivate Vaccinate Activate: An Effectiveness-Implementation Trial to Assess the Impact of a Multi-Component Community-Based Intervention to Increase RSV Vaccine Uptake Among Latino Older Adults

Who can join

Ages 18 and older · All sexes · Healthy volunteers welcome

Motivate Aim Inclusion Criteria:

* Age 50 years or older
* Self-identify as Latino/a/x and/or indigenous groups from Latin America
* Eligible for RSV vaccination per current CDC/ACIP recommendations
* Fluent in Spanish or English
* Has not received the RSV vaccine
* Has a cell phone
* Lives or works in San Francisco or Daly City
* Able to provide informed consent

Motivate Aim Exclusion Criteria:

* Intent to move outside of San Francisco or Daly City in the next year
* Nursing home resident
* Household member participating in Aim 1 or 2
* Unable to provide consent

Motivate Aim Inclusion Criteria:

* Age 18-49 years
* Self-identify as Latino/a/x and/or indigenous groups from Latin America
* Fluent in English or Spanish
* Has \>1 family member or friend 50 years or older who they have seen or spoken to for \>15 minutes in the last 6 months and who lives in the United States

Activate Trial Exclusion Criteria:

* Household member enrolled in Aim 1 or 2
* Unable to provide consent

About the study

In collaboration with community-based organizations, this study will focus on increasing RSV vaccine use among Latinos. The study will determine how effective community health worker counseling and text-message approaches are to (1) increase RSV vaccine use among older adults (Motivate phase) and (2) encourage younger adults to discuss RSV vaccination with their older friends and family members (Activate phase).

What is being tested

• Motivate Aim: CHW text message reminders and counseling (behavioral)
• Motivate Aim: CHW text message reminders only (behavioral)
• Activate Aim: CHW text message reminders and counseling (behavioral)
• Activate Aim: CHW text message reminders only (behavioral)

Sponsor: University of California, San Francisco · Participants: 750 · Started: Sep 10, 2025

Contact the study team

• RSV Uptake Study Coordinator · Phone: 415-608-8339

Official record on ClinicalTrials.gov — NCT07171164

Locations in the U.S.

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.