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LiveWell: An Adapted Dialectical Behavioral Therapy Skills Training Protocol for Patients Living With Metastatic Lung Cancer
Who can join
Ages 18 and older · All sexes
Full eligibility criteria
Inclusion Criteria: * Age ≥ 18 * AJCC Stage IV non-small cell lung cancer * Receiving treatment with non-curative intent or on active surveillance * English proficiency * Able to provide informed consent * National Comprehensive Cancer Network distress screening score ≥ 3/10 plus endorse at least 1 emotional concern. Exclusion Criteria: * Cognitive impairment * Untreated serious mental illness * Expected survival \< 6 months
About the study
In this pilot randomized controlled trial, patients with metastatic non-small cell lung cancer and at least mild distress (N=80) will be randomized to receive LiveWell, an adapted Dialectical Behavioral Therapy (DBT) Skills Training protocol) or Usual Care. The investigators will evaluate feasibility, acceptability, and preliminary efficacy of LiveWell to reduce distress (primary outcome) and improve psychological well-being, symptom burden, and quality of life (secondary outcomes). The investigators will explore emotion regulation as a potential mechanism of change.
What is being tested
- LiveWell: An Adapted Dialectical Behavioral Therapy Skills Training Program (behavioral)
Sponsor: Medical University of South Carolina · Participants: 80 · Started: Oct 15, 2026
Contact the study team
- Benjamin Axelrod · Phone: 843-876-2645
Official record on ClinicalTrials.gov — NCT07177846
Locations in the U.S.
| South Carolina | Medical University of South Carolina, Charleston |
Conditions
From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.