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Maximizing Laser Therapy Success for Port-Wine Birthmarks in Pediatric Patients
Recruiting
Who can join
2 Months – 18 Years · All sexes
Full eligibility criteria
Inclusion Criteria: * Diagnosis of Port Wine Stain. * Age Range: 2mo to 18 years of age. * Stable PWS: The port wine stain should be stable, meaning there is no active inflammation or infection present, and it should not be changing in size or color due to factors like injury or disease. * signed Consent: For ethical reasons, participants must be able to provide informed consent. In the case of minors, consent would generally be required from a parent or legal guardian. General Health: Participants should generally be in good health, with no contraindications for laser therapy, such as certain skin conditions, infections, or hypersensitivity to light. Exclusion Criteria: * severe allergies to anesthesia * active skin infections or inflammation * recent laser therapy * use of Photosensitizing medications * participation in other laser studies
About the study
In this study the investigators aim to optimize Port-Wine-Birthmark (PBW) laser therapy in children in order to reduce the number of laser treatments required for clearance and improve outcomes for refractory cases. This approach also seeks to reduce the frequency with which children require general anesthesia for treatment.
What is being tested
- Pulse Dye laser (device)
- Pulse Dye Laser (PDL) pulse width stacking (device)
- Pulse Dye Laser (PDL) followed by Nd:YAG (Neodymium-doped Yttrium Aluminum Garnet laser) laser. (device)
- IPL (Intense Pulsed Light) followed by Pulse Dye Laser (PDL) (device)
- Cupping followed by Pulse Dye Laser (PDL) (device)
Sponsor: University of Texas Southwestern Medical Center · Participants: 200 · Started: 2026-07
Contact the study team
- James R Seaward, MD · Phone: 214 456 5250
Official record on ClinicalTrials.gov — NCT07183644
Locations in the U.S.
| Texas | Children's Medical Center, Dallas Children's Medical Center, Plano |
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.