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Activities-based Locomotor Training in Children With Cerebral Palsy

Efficacy of Activities-based Locomotor Training in Children With Cerebral Palsy.

Who can join

Ages 2 to 6 · All sexes

Inclusion Criteria: To be eligible for this study, the child must be:

* • Able to hold their head upright for 5 seconds when supported at the trunk in sitting (the minimal amount of head control necessary for safe walking on the partial body weight support system during the AB-LT intervention);

  * Non-ambulatory or not walking as primary means of mobility;
  * Willing to attend the AB-LT intervention at Fortis Therapy Center in Dripping Springs, Texas for 3 hours/ day, 5 days/week, for 3 weeks; and
  * Willing to commit to a total of 7 weeks of the study, and to continue their usual care during the time period in which they are not enrolled in the AB-LT intervention.

Exclusion Criteria: The child must not have:

* • Surgery or botulinum toxin injections in the previous 6 months;

  * Uncontrolled epilepsy; and
  * Uncontrolled cardiovascular disease

About the study

This project aims to improve the quality of life and functional outcomes for young non-ambulatory children with Cerebral Palsy (CP) by investigating the efficacy of an Activities-Based Locomotor Training (AB-LT) program compared to usual care. By targeting the body structures, activities, and participation components of the World Health Organization's International Classification of Functioning, Disability, and Health (ICF) framework, this study seeks to enhance our understanding of neuroplasticity and motor learning in this population, offering a novel approach to rehabilitation. Results from this research will lead to more effective, individualized therapies that improve motor function, reduce disability, and ultimately lower the long-term healthcare needs associated with CP.

What is being tested

• Activities-based locomotor training (other)
• physical therapy (other)

Sponsor: Baylor University · Participants: 19 · Started: Jan 11, 2026

Contact the study team

• Elizabeth Ardolino, PhD, PT · Phone: 215-605-9319

Official record on ClinicalTrials.gov — NCT07184411

Locations in the U.S.

Conditions

• Cerebral Palsy

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.