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Study of MAR002 in Healthy Men

First in Human, Randomized, Blinded, Placebo-Controlled Single Ascending Dose and Multiple Dose Study of MAR002 in Healthy Men

Who can join

Ages 18 to 40 · Men · Healthy volunteers welcome

Inclusion Criteria:

1. Willingness to provide written informed consent
2. Age 18 to 40
3. Weight 55 to 95 kg
4. Body mass index (BMI) 18 to 30 kg/m2
5. Healthy men

Exclusion Criteria:

1. History of hypersensitivity to monoclonal antibodies or study drug
2. Participation in any other investigational drug study
3. History of cancer
4. Recent acute illness
5. Positive test for HIV, hepatitis B/C
6. History of substance abuse or nicotine use
7. Recent blood donation
8. History of pituitary disorder
9. Any condition that prevents the participant from complying with study procedures

About the study

Evaluate the safety and tolerability of subcutaneous (SC) administration of MAR002 in healthy men

What is being tested

• MAR002 (drug)
• Placebo (drug)

Sponsor: Marea Therapeutics · Participants: 45 · Started: Aug 11, 2025

Contact the study team

• Andrew Lane · Phone: 415-766-3610

Official record on ClinicalTrials.gov — NCT07195175

Locations in the U.S.

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.