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Multi-site Study to Look at Tooth Wear and Tooth Sensitivity and the Risk Factors Associated.

RecruitingObservational study

Erosive Tooth Wear, Dentin Hypersensitivity and Associated Risk Factors: An Observational, Cross-Sectional, Multi-Site, Epidemiological Study in the U.S." IU IRB# 28041

Who can join

Ages 18 and older · All sexes

Full eligibility criteria
Inclusion Criteria:

1. Be aged 18 or over, of either gender.
2. Be attending a regularly scheduled appointment at the dental school.
3. Provide voluntary, written informed consent.
4. Understand and be willing, able and likely to comply with all study procedures and restrictions.
5. Be in good health (see exclusion criteria below).
6. Have a minimum of 10 teeth not including implants or teeth with crowns or bridges.

Exclusion Criteria:

1. Have any medical condition that could be expected to interfere with the subject's safety during the study period (including temporomandibular disorders).
2. Be incapable of responding to the questions.
3. Be an employee or a family relative of an employee of the sponsor.
4. Be using maxillary or mandibular orthodontic appliances, except lingual bar.
5. Have used analgesic (pain relieving) drugs or have used a topical analgesic in the preceding 12 h

About the study

The goal of this observational study is to learn about tooth wear and tooth sensistivity and reasons for these conditions in five locations throughout the United States. The main question it aims to answer is:

The main objective of this study is to determine tooth wear and tooth sensitivity in adults in the U.S., and to investigate their association with risk factors

What is being tested

Sponsor: Indiana University · Participants: 2,500 · Started: Feb 19, 2026

Contact the study team

Official record on ClinicalTrials.gov — NCT07195357

Locations in the U.S.

IndianaIndiana University School of Dentistry - Oral Health Research Institute, Indianapolis

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.