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Treatment of Borderline Personality Disorder With rTMS
CLINICAL TRIAL: Treatment of Borderline Personality Disorder by Targeting Ventrolateral Prefrontal-amygdala Circuit With Network-based Neuronavigated Transcranial Magnetic Stimulation
Who can join
Ages 18 to 65 · All sexes
Full eligibility criteria
* Age of 18-65 * DSM-5 Diagnosis of BPD based upon a psychiatric evaluation and ZAN-BPD * Fluent English speaker * Signed informed consent
About the study
This project studies the effectiveness of brain stimulation on borderline personality disorder (BPD) symptoms. This study is blinded, randomized and will enroll up to 30 participants.
Participant will be consented for the study remotely via a secure internet platform called Zoom.
Participants will undergo up to 2 MRI scans, 2 brain wave recording sessions and up to 30 brain stimulation treatments, and complete symptom assessments and cognitive behavioral tasks on a computer. Participation requires minimum of 17 in person visits over the course of 2.5 months.
Participants are randomly assigned active or sham brain stimulation. Participants who received sham brain stimulation have the option to receive additional 15 active brain stimulation session.
What is being tested
- Transcranial Magnetic Stimulation (TMS) (device)
Sponsor: University of California, Los Angeles · Participants: 30 · Started: Mar 1, 2025
Contact the study team
- Elizabeth Pinkerton · Phone: 310-794-0331
Official record on ClinicalTrials.gov — NCT07197502
Locations in the U.S.
| California | Semel Institute for Neuroscience and Human Behavior at UCLA, Los Angeles Semel Institute/ UCLA TMS, Los Angeles |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.