Home › Sudden Cardiac Arrest › NCT07197918

Identification of Brain Injury Using Portable MRI

Prospective Identification of Hypoxic Ischemic Brain Injury Using Portable Magnetic Resonance Imaging

Who can join

Ages 18 and older · All sexes

Inclusion Criteria:

* Unresponsive immediately after ROSC from IHCA or OHCA
* Age ≥ 18 years of age
* Conventional MRI is clinically indicated
* Treatment with temperature control

Exclusion Criteria:

* MRI contraindication according to the American Heart Association guidelines
* Inability to tolerate supine positioning for 30 minutes
* Diffuse loss of grey-white differentiation and sulcal effacement on head computed tomography within 6 hours of ROSC

About the study

The goal of this study is to look for brain injury in patients who had a cardiac arrest, using portable brain imaging. The portable nature of this test will also allow for serial imaging so the investigators can understand how brain injury changes over days. The results of this study may allow for bedside imaging to be available at centers without specialized imaging centers and may identify markers of brain injury that help to select the patients most likely to benefit for clinical trials.

What is being tested

• portable MRI scanner (device)

Sponsor: Yale University · Participants: 60 · Started: Dec 2, 2025

Contact the study team

• Rachel Beekman, MD · Phone: 516-965-4251
• Emily Gilmore, MD, MS · Phone: 203-314-0555

Official record on ClinicalTrials.gov — NCT07197918

Locations in the U.S.

Conditions

• Sudden Cardiac Arrest
• Brain Hypoxia-Ischemia

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.