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Retropubic Hydrodissection and Trocar-induced Bladder Perforation During Retropubic Midurethral Slings

Does Retropubic Hydrodissection Decrease Trocar-induced Bladder Perforation Rates During Placement of Retropubic Midurethral Slings? A Randomized Controlled Trial

Who can join

Ages 18 and older · Women · Healthy volunteers welcome

Inclusion Criteria:

* scheduled for retropubic midurethral sling

Exclusion Criteria:

* cognitive or intellectual impairment that would hinder ability to complete questionnaires or be consented
* having concurrent surgery for malignancy

About the study

Retropubic midurethral slings are a common and effective treatment for stress urine incontinence. The trocar that is attached to the mesh material can hit the bladder which is called a perforation. While there are no known long-term adverse outcomes from trocar-induced bladder perforations, it can prolong operative time and bleeding. At academic institutions, it has been reported that trocar-induced perforations occurs in the range of 14-34% of the time. This study is a randomized controlled trial to see if an intervention can decrease trocar-induced bladder perforation rates. The primary outcome of this study is to measure trocar-induced bladder perforations in subjects undergoing a retropubic midurethral sling. Subjects would be randomized to either receive the hydrodissection in a standardized manner or to not receive it. Secondary outcomes include bothersome urinary symptoms, pain, estimated blood loss during surgery, and voiding trial results

What is being tested

• retropubic hydrodissection (procedure)

Sponsor: University of Massachusetts, Worcester · Participants: 300 · Started: Apr 3, 2025

Contact the study team

• Emily Wu, MD · Phone: 508-334-9840

Official record on ClinicalTrials.gov — NCT07208682

Locations in the U.S.

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.