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Dopamine and Sensorimotor Function in Stuttering

Who can join

Ages 18 to 65 · All sexes · Healthy volunteers welcome

Inclusion Criteria:

* native speakers of American English
* for adults who stutter, presence of stuttering will be confirmed, with onset before age 6 years
* Normal hearing
* Ages of 18 to 65 years
* healthy adults without hearing-language difficulties

Exclusion Criteria:

* self-reported speech-language-hearing difficulties other than stuttering
* self-reported neurological or psychological problems
* other medications (drugs that affect dopaminergic system and/or benzodiazepines)

About the study

This study is being done to understand the effect of aripiprazole on adults who stutter. Stuttering is a disorder that affects speech fluency. This study aims to understand sensorimotor pathways of stuttering and possible interventions.

What is being tested

• Aripiprazole 10 MG (drug)
• Placebo (drug)

Sponsor: University of California, San Francisco · Participants: 25 · Started: Sep 30, 2025

Contact the study team

• Natalie Brunwin, MS · Phone: 4154766888

Official record on ClinicalTrials.gov — NCT07215884

Locations in the U.S.

Conditions

• Stuttering

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.