Home › Hodgkin Lymphoma › NCT07222345

Feasibility of High Intensity Interval Training in Survivors of Childhood, Adolescent, and Young Adult Hodgkin Lymphoma

Who can join

Ages 10 to 25 · All sexes

Inclusion Criteria:

* Participant has been diagnosed with Hodgkin lymphoma between the ages of 10 to 25 years.
* Participant is between the ages of \>10 and \<25 years old the time of enrollment.
* Participant has completed treatment (end of chemotherapy for those not receiving radiation therapy or end of radiation therapy) for Hodgkin lymphoma within 24 months prior to enrollment and recovered from any acute treatment-related adverse events.
* Participant has been medically cleared to participate in physical activity.
* Participant verbalizes understanding of directions for use of the web-based platform on the study provided iPad and heart rate monitor.

Exclusion Criteria:

* Participant has evidence of relapsed disease.
* Participant has a diagnosis of acute heart failure.
* Participant reports currently participating in HIIT training or \>420 minutes per week of moderate to vigorous physical activity.
* Female participant who is currently pregnant.

About the study

This pilot study evaluates the feasibility of a 12-week high intensity interval training (HIIT) program in survivors of childhood, adolescent, and young adult Hodgkin lymphoma within 24 months of completing treatment. Preliminary efficacy of the HIIT intervention for improved cardiorespiratory fitness, body composition, physical function, autonomic response to exercise, peripheral neuropathy, biological aging markers, and physical activity will also be evaluated.

Primary Objective:

To determine the feasibility of a 12-week high intensity interval training (HIIT) program in survivors of childhood, adolescent, and young adult Hodgkin lymphoma within 24 months of completing treatment.

Feasibility will be assessed by:

* Participation Rate: Number of eligible survivors approached who enroll. * Completion Rate: Number of scheduled HIIT sessions attended and number of enrolled participants who complete post-intervention testing.

What is being tested

• High Intensity Interval Training (HIIT) (behavioral)

Sponsor: St. Jude Children's Research Hospital · Participants: 20 · Started: Jun 8, 2026

Contact the study team

• Amy Berkman, MD · Phone: 888-226-4343

Official record on ClinicalTrials.gov — NCT07222345

Locations in the U.S.

Conditions

• Hodgkin Lymphoma

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.