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Impact of Smell Testing on Health Outcomes

RecruitingPhase 2Healthy volunteers welcome

Validating the Impact of Smell Testing on Health Outcomes and Provider Engagement.

Who can join

Ages 7 and older · All sexes · Healthy volunteers welcome

Full eligibility criteria
Inclusion Criteria:

\- Can read and understand English and have access to a reliable internet connection and a smart device or computer for the duration of the experimental sessions, unless they are part of community events in which smart devices are provided

Exclusion Criteria:

\- Known intolerance or allergy to any of the odor stimuli used

About the study

Smell dysfunction is frequent yet neglected. The sense of smell plays a crucial role in signaling disease, safety, and overall quality of life. However, the significance of a functional sense of smell in terms of health and well-being is often overlooked until one experiences a loss of smell due to injury or disease. Research demonstrates that individuals are often not self-aware of their smell dysfunction (i.e. they do not spontaneously report smell dysfunction as a symptom), especially if the changes are gradual, as in normal aging. Patients with smell dysfunction experience a marked reduction in quality of life, poor mental health, nutritional health, and brain health as well as increased 5- and 10-year mortality in older adults. This study explores whether or not enabling healthcare providers to offer resources and guidance on coping strategies for smell dysfunction improves health and wellbeing in those who experience it.

What is being tested

Sponsor: Monell Chemical Senses Center · Participants: 1,000 · Started: May 29, 2026

Contact the study team

Official record on ClinicalTrials.gov — NCT07222891

Locations in the U.S.

PennsylvaniaMonell Chemical Senses Center, Philadelphia

Conditions

From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.