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A Multicenter Prospective Observational Cohort Study Evaluating the Impact of Cancer-Directed Treatment and Medication Use, Including Cannabis Use, in Multiple Myeloma Patients

RecruitingObservational studyHealthy volunteers welcome

Who can join

Ages 18 and older · All sexes · Healthy volunteers welcome

Full eligibility criteria
Inclusion Criteria:

* \* Documented informed consent of the participant

  * Age: ≥ 18 years
  * ECOG ≤ 3
  * Ability to read and understand English
  * Patient must be newly diagnosed with a histologically confirmed multiple myeloma
  * Patients may have started first line therapies and received up to four cycles
  * HCP SURVEY: Documented informed consent of the participant
  * HCP SURVEY: Age: ≥ 18 years
  * HCP SURVEY: Licensed physician, physician assistant, nurse practitioner, or registered nurse
  * HCP SURVEY: Currently practicing in oncology or providing direct care to oncology patients
  * HCP SURVEY: Able to read and understand English
  * HCP SURVEY: Affiliation with City of Hope

Exclusion Criteria:

* \* Patients may not have completed five cycles of first line therapy or undergone any second line therapy

  * Other active malignancy
  * Patients may not have undergone autologous hematopoietic stem cell transplantation
  * Unable to comply with the study assessments
  * HCP SURVEY: Reports directly to study PI (Dr. Richard Lee)
  * HCP SURVEY: Member of the study team or involved in survey design or analysis
  * HCP SURVEY: Individuals with a real or perceived conflict of interest that could bias survey responses

About the study

This study assesses the impact of cannabis (also commonly called marijuana, weed, or THC) use on quality of life among patients with multiple myeloma who are receiving chemotherapy. It also evaluates the potential benefits and harms of cannabis use.

What is being tested

Sponsor: City of Hope Medical Center · Participants: 700 · Started: Jan 21, 2026

Contact the study team

Official record on ClinicalTrials.gov — NCT07225738

Locations in the U.S.

ArizonaCTCA at Western Regional Medical Center, Goodyear (Not yet recruiting)
CaliforniaCity of Hope Medical Center, Duarte
City of Hope Seacliff, Huntington Beach (Not yet recruiting)
City of Hope at Irvine Lennar, Irvine
City of Hope at Long Beach Elm, Long Beach (Not yet recruiting)
City of Hope at Newport Beach Fashion Island, Newport Beach (Not yet recruiting)
City of Hope South Pasadena, South Pasadena (Not yet recruiting)
City of Hope Upland, Upland (Not yet recruiting)
City of Hope West Covina, West Covina (Not yet recruiting)
GeorgiaCity of Hope Atlanta Cancer Center, Newnan (Not yet recruiting)
IllinoisCity of Hope at Chicago, Zion (Not yet recruiting)

Conditions

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.