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Comprehensive Toileting Program

Comprehensive Toileting Programming: Enuresis Treatment to a Randomized Clinical Trial of a Caregiver-Mediated Multidisciplinary Intervention for Encopresis

Who can join

Ages 5 to 12 · All sexes

Inclusion Criteria

* Age 5 to 12
* Diagnosis of an intellectual or developmental delay (excluding individuals with ADHD alone)
* Encopresis (more than 1 incontinent BM a week)
* Required for pre-randomization phase only: Enuresis (\> 1 incontinent urination per day when on a consistent toileting sit schedule)
* At least one caregiver who speaks and understands English

Exclusion Criteria:

* Unresolved medical condition that would impede toilet training (e.g., interference with sphincter control, short gut syndrome, urinary tract or gastrointestinal infection, unexplained diarrhea, recent intestinal surgery, inflammatory bowel disease)
* Failed intensive toileting treatment in the past 2 yrs with protocols akin to study
* Current serious behavioral or psychiatric disorder that requires another treatment
* Current or planned other intervention (behavioral or medical) for incontinence

About the study

The current study aims to monitor fecal continence after autistic youth complete enuresis treatment and for individuals who continue to experience encopresis after acquiring urine continence, evaluate a caregiver-mediated version of a Multidisciplinary Intervention for Encopresis (CM-MIE) delivered via telehealth to determine efficacy in a randomized clinical trial.

What is being tested

• Glycerin Suppository (drug)
• Behavioral strategies (behavioral)

Sponsor: Emory University · Participants: 150 · Started: Jun 1, 2026

Contact the study team

• Mindy Scheithauer, PhD · Phone: 404-785-9322

Official record on ClinicalTrials.gov — NCT07226739

Locations in the U.S.

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.