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Moving Forward With Myeloma: A Lifestyle Intervention for Individuals With Multiple Myeloma

Recruiting

Who can join

Ages 18 and older · All sexes

Full eligibility criteria
Inclusion Criteria:

1. Adult (≥ 18 years)
2. Diagnosed with MM at least one year prior to study enrollment
3. Has access to a cell phone
4. Be deemed "clinically stable" by their physician guided by the following:

   1. no near-term changes in planned myeloma-directed therapy anticipated. (e.g., patient who is 3 months from autologous stem cell transplant just starting on maintenance lenalidomide is eligible since maintenance is planned therapy following transplant)
   2. no new significant myeloma symptoms (e.g., fractures) meriting changes in anti-neoplastic therapies; AND
   3. stable performance status (ECOG 0-2)
5. No reports of severe pain \> Grade 3 \[defined by the NCI CTCAE as tumor, neurologic, bone, or other pain interfering with self-care ADLs (bathing, dressing, toileting, continence, feeding)\].
6. Able to participate in moderate PA and strength training per clinician approval and confirmed by participant
7. Able to understand and willing to sign a written informed consent document
8. English proficient for reading and writing

Exclusion Criteria:

1. Individuals with \<6 months of life anticipated, coexistent amyloidosis, and/or receiving appetite stimulants will not be approached
2. Fully adherent to the ACS nutrition and physical activity guidelines
3. Currently pregnant or lactating, or anticipating pregnancy
4. On another interventional clinical trial that precludes co-enrollment
5. Psychiatric or other clinical conditions that preclude study compliance
6. Other important medical or safety considerations at the discretion of the investigator(s) and/or approving clinician

About the study

The purpose of this project is to evaluate the impact of a 16-week lifestyle program that promotes changes in eating and exercise patterns. The main questions the study will answer are:

Do improvements in eating and exercise patterns lead to improved physical function, quality of life and blood biomarkers of biologial aging among individuals with multiple myeloma? Participants will complete study activities 3-4 times during the study.

1. In-person assessment to measure physical function, height/weight, body composition, and includes a blood draw 2. Surveys completed online or on paper at home

What is being tested

Sponsor: Medical College of Wisconsin · Participants: 184 · Started: Jan 30, 2026

Contact the study team

Official record on ClinicalTrials.gov — NCT07236502

Locations in the U.S.

IllinoisLoyola University Chicago, Maywood
WisconsinMedical College of Wisconsin, Milwaukee

Conditions

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.