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The Impact of Irrisept in Reducing Urinary Tract Infection During Urethral Catheter Removal.

To Determine the Efficacy of Irrisept in Reducing Urinary Tract Infection During Urethral Catheter Removal.

Who can join

Ages 18 and older · All sexes · Healthy volunteers welcome

Inclusion Criteria:

1. Presenting to the urology clinic for catheter removal
2. Must be 18 years or older.
3. The patient must be able to understand and willing to provide informed consent as described in this study protocol.
4. Must be willing to complete a post-catheter removal survey

Exclusion Criteria:

1. Allergy or adverse reaction to chlorohexidine gluconate
2. Under the age of 18
3. Refuse to provide informed consent
4. On antibiotic therapy for any indication.
5. Women who are pregnant or breastfeeding
6. Signs of skin or systemic infection
7. Patients undergoing catheter exchange

About the study

Given the high burden of post-catheter removal UTIs, this study aims to evaluate Irrisept instillation as a non-antibiotic intervention to reduce infection rates. By comparing Irrisept to saline irrigation, the study will provide critical insights into the efficacy of antiseptic bladder irrigation in preventing UTIs while minimizing antibiotic use. If successful, this approach could lead to new clinical guidelines for catheter removal protocols, improving patient outcomes and reducing healthcare costs.

What is being tested

• 0.05% Chlorhexidine Gluconate (other)
• Normal Saline (other)

Sponsor: Ohio State University · Participants: 300 · Started: Jan 1, 2026

Contact the study team

Official record on ClinicalTrials.gov — NCT07239219

Locations in the U.S.

Conditions

• Urinary Tract Infections

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.