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Dome-Only Aneurysm Coiling in Severe Aneurysmal Subarachnoid Hemorrhage

Dome-Only Aneurysm Coiling in Severe Aneurysmal Subarachnoid Hemorrhage Observational Study

Who can join

Ages 18 and older · All sexes

Inclusion Criteria:

* 18 years or older
* CT confirmed aSAH with an angiographically detected aneurysm
* World Federation of Neurological Sciences (WFNS) aSAH grade 3-5 aneurysm
* LAR available and gives consent within 72 hours after the onset of aSAH (or last known normal

Exclusion Criteria:

* Patients whose aneurysm judged appropriate for balloon-assisted coiling
* Patients whose aneurysm is bleeding from the "neck"
* Patients who are clinically judged to suffer imminent death within 24 hours.
* Pregnancy or positive urine pregnancy test

About the study

The DOME study is a clinical trial exploring a new treatment approach for patients who suffered a severe brain bleed due to an aneurysm.

Sponsor: University of Louisville · Participants: 30 · Started: Mar 12, 2026

Contact the study team

Official record on ClinicalTrials.gov — NCT07250958

Locations in the U.S.

Conditions

• Subarachnoid Hemorrhage

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.