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Stress and Anxiety Effects on Valuation
RecruitingHealthy volunteers welcome
Who can join
Ages 18 to 65 · All sexes · Healthy volunteers welcome
Full eligibility criteria
Inclusion Criteria: Aims 1-3: To be eligible for participation in this study, an individual must meet all of the following criteria: * 18-65 years of age * Able to speak, read, and write fluently in English * Be willing and able to follow study procedures and provide informed consent. Aim 4: To be eligible for participation in this study, an individual must meet all of the following criteria: * 18-65 years of age * Diagnosis of GAD * Able to speak, read, and write fluently in English * Be willing and able to follow study procedures and provide informed consent. Exclusion Criteria: Aims 1-3: Individuals will be excluded from participation if any of the following criteria are met: * History of or medication for neurologic or psychiatric disease * High-blood pressure or heart condition * Diabetes, food allergies, metabolic disorders or history of eating disorder * Use of corticosteroids or beta-blockers * Pregnancy Aim 4: Individuals will be excluded from participation if any of the following criteria are met: * High-blood pressure or heart condition * Diabetes, food allergies, metabolic disorders or history of eating disorder * Use of corticosteroids or beta-blockers * Lifetime history of bipolar disorder or any psychotic disorder; substance use disorder in past 3 months; eating disorder in past 6 months; current major depressive disorder (past is allowed) * Active suicidal ideation with plan and intent (indicated by score \>=4 on the Columbia Suicide Severity Scale) * Not on stable dose of psychiatric medication for at least 4 weeks prior to study participation * Pregnancy
About the study
The purpose of this study is to understand how stress, anxiety, and negative affect change learning and decision-making processes. The primary objective is to assess two forms of decision-making-reward adaptation and emotion prediction errors-differ as a function of stress and anxiety. The secondary objectives are to assess how individual differences measured in our studies relate to these decision variables.
What is being tested
- Socially Evaluated Cold Pressor Task (SECPT) (behavioral)
- Non-Stressful Control Task (behavioral)
Sponsor: NYU Langone Health · Participants: 200 · Started: Dec 18, 2025
Contact the study team
- Candace Raio, PhD · Phone: 212-404-4223
- Ariana Wahab · Phone: 212-404-3850
Official record on ClinicalTrials.gov — NCT07252947
Locations in the U.S.
| New York | NYU Langone Health, New York |
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.