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RNA Sequencing of Discarded Tracheal Stenosis Tissue to Characterize Cellular and Molecular Pathogenesis

RecruitingObservational study

Who can join

Ages 18 to 80 · All sexes

Full eligibility criteria
Inclusion Criteria:

* Patients with benign tracheal stenosis

Exclusion Criteria:

* Malignancy. active infection

About the study

Benign tracheal stenosis is a rare but potentially life-threatening condition, typically resulting from fibroinflammatory scarring. It can be secondary to iatrogenic etiologies such as intubation or tracheostomy , as well as autoimmune diseases and being idiopathic. Patients typically undergoes endoscopic or surgical interventions to open up the airways. This project will analyze resected or biopsied tissue from patients with benign tracheal stenosis to define disease-specific RNA expression profiles.

What is being tested

Sponsor: University of Maryland, Baltimore · Participants: 10 · Started: Sep 11, 2025

Contact the study team

Official record on ClinicalTrials.gov — NCT07258784

Locations in the U.S.

MarylandUniversity of Maryland, Baltimore

Conditions

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.