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Facilitating Lactation Through Optimized Workflows - Evaluating the Efficiency of Pumping Protocols and Cellular Mechanisms of Milk Production

Who can join

Ages 18 to 45 · All sexes · Healthy volunteers welcome

Inclusion Criteria:

* English-speaking
* Lactating parents of singleton, term infants less than 3 months of age
* Intend to breastfeed and are breastfeeding (at the breast) at least 3 times per day

Exclusion criteria:

* Twins and other multiples
* Contraindications to or unable to breastfeed
* Major congenital anomaly or unexpected surgery
* Elevated maternal depression
* Low milk transfer
* No electricity or smartphone access

About the study

The purpose of this study is to evaluate the effectiveness of two different breast pumping protocols in increasing milk production among lactating individuals diagnosed with primary low milk supply, and to investigate the associated molecular, hormonal, and inflammatory mechanisms driving milk output.

What is being tested

• Pumping frequency intervention (other)

Sponsor: University of Rochester · Participants: 225 · Started: May 7, 2026

Contact the study team

Official record on ClinicalTrials.gov — NCT07260968

Locations in the U.S.

Conditions

• Breastfeeding

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.