Clinical Performance of Nobel N1 System

Inclusion Criteria:

* Males and females, age 18 or older

  * Can provide an Informed Consent in English.
  * Absence of a single posterior tooth in mandible or maxilla with presence of natural neighboring teeth (except for second molar which only requires presence of first molar)
  * Presence of antagonist teeth
  * Possibility and will for an immediate restoration.
  * Systemic health recorded as an American Society of Anesthesiologists (ASA) I or II

Exclusion Criteria:

* · Unavailability to attend the follow-up visits.

  * A systemic contraindication for oral surgical procedures; ASA III or IV.
  * Pregnancy or nursing on screening or before the surgical procedure.
  * Diseases that could alter healing or bone metabolism (uncontrolled diabetes, diagnostic osteoporosis, etc.),
  * Taking medications that are altering healing or bone metabolism (bisphosphonates, long-time corticosteroids intake, RANK inhibitors, etc.)
  * Alcohol or drug abuse.
  * Current heavy smoking behavior (≥10 cigarettes/day).
  * Radiation therapy to the head or neck region.
  * Pathology in the implant planned sites that prevent implant placement.
  * Current diagnosis of Diabetes, which is uncontrolled (\>7 HbA1C).
  * Need for sinus lift or vertical bone augmentation
  * Previously failed implant site