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Examining Bronchial Hyperresponsiveness in Primary Ciliary Dyskinesia

A Multi-center Study Examining Bronchial Hyperresponsiveness in Primary Ciliary Dyskinesia

Who can join

Ages 6 and older · All sexes · Healthy volunteers welcome

Inclusion Criteria:

* Confirmed diagnosis of PCD per standard diagnostic criteria4 and positive genetics
* Age greater than or equal to 6 years (no upper age limit)
* Any gender or race
* Able to perform pulmonary function testing (historical documentation of reversibility will be accepted)

Exclusion Criteria:

* history of current pneumothorax
* inability to perform pulmonary function testing

About the study

The purpose of this study is to look at children with PCD and see if they have another condition called "bronchial hyperresponsiveness".

What is being tested

• Lung Function Testing (procedure)
• Phlebotomy (procedure)
• Allergy skin prick testing (procedure)
• Methacholine Challenge (procedure)

Sponsor: Indiana University · Participants: 40 · Started: May 4, 2023

Contact the study team

• Fanmuyi Yang, PhD · Phone: 317-274-8895
• Lisa Bendy · Phone: 317-278-7152

Official record on ClinicalTrials.gov — NCT07288827

Locations in the U.S.

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.