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A Mobile Patient Health Technology Intervention for Improving Lung Cancer Screening Rates in Eligible High Risk Patients
A Pragmatic Randomized-Controlled Learning Health System Trial
Who can join
Ages 50 to 77 · All sexes
Full eligibility criteria
Inclusion Criteria: Eligible patients will: * Meet the Medicare criteria for lung cancer screening, as updated in February 2022: * Age 50 - 77 years * Smoked at least 20 pack years * Current smoker or quit smoking within the past 15 years * Be established with a primary care provider within the Atrium Health Wake Forest Baptist health network (defined as having completed at least 1 primary care appointment in the past 6 months or have completed at least 2 primary care appointments within the past 18 months or being scheduled to see a health network primary care provider within the next 30 days). * Have a patient portal account or cellphone number listed in the electronic health record * Have a North Carolina address listed in the electronic health record Exclusion Criteria: The following patients will be excluded: * Patients flagged as needing a language interpreter in the electronic health record for any language other than Spanish (electronic messages and intervention are deliverable in English or Spanish only) * Those for whom lung cancer screening would be or may be inappropriate: electronic health record Prior history of lung cancer electronic health record Chest CT within the last 12 months electronic health record Those meeting the HEDIS COL-E measure exclusion criteria based on significant comorbidities and/or frailty.
About the study
To evaluate the real-world effectiveness and implementation strategies for mPATH-Lung, investigators propose a pragmatic, randomized controlled trial across an academic Learning Health System. The trial will contrast several approaches to participant outreach and will specifically target engaging fully powered cohorts of racial/ethnic minorities and rural residents.
What is being tested
- Portal Message with Reminder Text Messages (other)
- Text Message with Reminder Text Messages (other)
- Portal message only (other)
- Usual Care (other)
Sponsor: Wake Forest University Health Sciences · Participants: 27,000 · Started: Mar 25, 2026
Contact the study team
- Study Coordinator · Phone: 704-355-2000
Official record on ClinicalTrials.gov — NCT07322367
Locations in the U.S.
| North Carolina | Atrium Health Wake Forest Baptist, Winston-Salem |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.