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HUD Surgical Guidance for Toric Alignment
Clinical Evaluation of a Novel Intraoperative Guidance System for Accurate Toric IOL Positioning in Cataract Surgery
Who can join
Ages 18 and older · All sexes
Full eligibility criteria
Inclusion criteria: * Patients undergoing uncomplicated cataract surgery with toric IOL implantation, * Eyes implanted with a toric IOL. Exclusion criteria: * Ocular comorbidity likely to impair postoperative visual acuities, or * History of ocular trauma or zonular instability, or * Previous refractive surgery, or * Irregular corneal astigmatism or keratoconus, or * Patients with physical or intellectual disabilities that may prevent reliable fixation or comprehension (e.g. Down's Syndrome, Parkinson's Disease), or * Patients with unreliable biometry measurements, or * Severe dry eye disease or ocular surface disease.
About the study
This study aims to assess the accuracy of toric intraocular lens (IOL) alignment axes as calculated and displayed by a novel digital guidance system. In addition, it evaluates the time required to initiate surgical guidance and postoperative refractive astigmatism following toric IOL implantation.
This single-surgeon, single-site, prospective, non-invasive observational study evaluated the accuracy of toric IOL alignment axes calculated and displayed by the digital guidance system (Cassini Technologies, B.V.) in 100 eyes. The intraoperatively calculated alignment axes were compared to preoperative measurements to assess their accuracy (in degrees). Postoperative outcomes, including residual refractive astigmatism (diopters) and visual acuity (Snellen), were recorded at 1 month postoperatively.
What is being tested
- Cassini Guidance (device)
Sponsor: Gainesville Eye Associates · Participants: 100 · Started: Nov 4, 2025
Contact the study team
- Dr. Clayton Blehm Blehm, MD · Phone: (770) 532-4444
Official record on ClinicalTrials.gov — NCT07325188
Locations in the U.S.
| Georgia | North Georgia Eye Associates, Gainesville |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.