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Aspiration Thrombectomy Using the Symphony or Prodigy System

Long-Term CLinical Evaluation of Aspiration ThRombectomy Using the Symphony or ProdIgy Thrombectomy System - CLEAR-IT

Who can join

Ages 18 and older · All sexes

Inclusion Criteria:

1. Subject is ≥ 18 years of age
2. Subject is willing and able to comply with the follow-up schedule specified in this protocol
3. Subject is willing and able to provide written informed consent prior to any study-related data collection
4. Subject has a planned procedure, involving the use of Imperative Care vascular devices within their intended use

Exclusion Criteria:

1. Subjects with any contraindications per the applicable Instructions for Use
2. Subject with life expectancy of less than 1 year
3. In the opinion of the Investigator, the patient is not a suitable candidate for intervention with Imperative Care devices
4. Subject who may be unable to complete study follow-up
5. Peripheral Venous Cohort ONLY: Presence of thrombus extending more than 2 cm into the IVC on imaging

About the study

The study is designed to evaluate the short-term and long-term clinical performance and safety of the Symphony and Prodigy thrombectomy systems used in endovascular procedures across the peripheral or pulmonary vasculature.

What is being tested

• Prodigy Thrombectomy System (device)
• Symphony Thrombectomy System (device)
• Symphony Thrombectomy System (device)

Sponsor: Imperative Care, Inc. · Participants: 750 · Started: Feb 13, 2026

Contact the study team

• Sylvie Akiel-Fu, MPH · Phone: 917-375-4735

Official record on ClinicalTrials.gov — NCT07350499

Locations in the U.S.

Conditions

• Venous Thromboembolism
• Pulmonary Embolism
• Blood Clots
• Thromboembolism

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.