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Inspiratory Muscle Training for Breast Cancer Patients on Chemotherapy

Recruiting

Effects of Inspiratory Muscle Training Among Breast Cancer Patients Undergoing Active Treatment (IMACT)

Who can join

Ages 18 and older · Women

Full eligibility criteria
Inclusion Criteria:

* Age ≥ 18 years
* Within 3 weeks of starting chemotherapy for an early-stage breast cancer diagnosis
* Able to exercise independently without needing support
* Ability to read, speak, understand English

Exclusion Criteria:

* Metastatic breast cancer
* Unwilling or unable to follow protocol requirements
* Any significant health condition which in the investigator's opinion increases the risks of participation or makes the participant unsuitable for the study

About the study

This clinical trial studies whether breathing exercises for the muscles that help with breathing air in, inspiratory muscle training (IMT), works to improve breathing muscle strength, shortness of breath, and physical activity levels in women who are receiving chemotherapy for early-stage breast cancer (BC). Cancer and/or treatments for BC can directly result in muscle wasting that involves breathing muscles, skeletal muscles or heart muscles. Pain, weakness, shortness of breath, and side effects of cancer treatment may lead to lower physical activity levels. IMT involves breathing exercises using a small hand-held device. The device makes it a little harder to breathe in, which may help strengthen breathing muscles. IMT may be an effective way to improve breathing muscle strength, shortness of breath, and physical activity levels in women who are receiving chemotherapy for early-stage BC.

What is being tested

Sponsor: Ohio State University Comprehensive Cancer Center · Participants: 58 · Started: Feb 16, 2026

Contact the study team

Official record on ClinicalTrials.gov — NCT07386444

Locations in the U.S.

OhioOhio State University Comprehensive Cancer Center, Columbus

Conditions

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.