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Feasibility and Clinical Utility of Paired Non-Invasive Hemodynamic and Tissue Oximetry Monitoring to Detect Limb Ischemia in Lithotomy-Positioned Surgeries

Who can join

All ages · Women · Healthy volunteers welcome

Inclusion Criteria:

1. Adult patients
2. Undergoing minimally invasive pelvic surgery (such as hysterectomy, myomectomy, or endometriosis surgery)
3. Surgery performed in lithotomy position
4. Expected surgical duration \> 2 hours as determined by the primary surgeon

Exclusion Criteria:

1. Pregnant patients
2. Procedures expected to last \< 2 hours
3. Open surgical approaches
4. Minor procedures
5. Known allergy or sensitivity to adhesives used for monitoring sensors
6. Vulnerable populations (incarcerated, elderly or pregnant)

About the study

The LIMB Study is a prospective, observational pilot study evaluating the feasibility of combined non-invasive hemodynamic and lower-limb tissue oximetry monitoring during prolonged minimally invasive pelvic surgeries performed in lithotomy position. Thirty patients will undergo continuous intraoperative monitoring, with the primary outcome being the frequency and duration of tissue oxygen desaturation events and secondary outcomes examining correlations with postoperative limb pain, sensation, and motor function. The study is non-interventional, poses minimal risk, and aims to generate preliminary data to inform future strategies for early detection and prevention of limb ischemia and well-leg compartment syndrome

What is being tested

• Lower-Extremity Perfusion Monitoring (other)

Sponsor: The University of Texas Health Science Center, Houston · Participants: 30 · Started: Jan 29, 2026

Contact the study team

• Randa Jalloul, MD, MS · Phone: 7134867700

Official record on ClinicalTrials.gov — NCT07387653

Locations in the U.S.

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.