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Patient and Caregiver Perspectives on Intravesical Instillations for Urinary Symptoms

RecruitingObservational study

Intravesical Gentamicin Coupled With Lactobacillus Rhamnosus for Urinary Health- Early Career

Who can join

Ages 18 and older · All sexes

Full eligibility criteria
Inclusion Criteria:

Criteria for patients:

* Age 18+
* Diagnosis of NLUTD
* Chronic catheter usage (minimum 6 months), either intermittent catheterization or indwelling catheter
* Community-dwelling
* Experience using intravesical Lactobacillus, gentamicin, or combination of the two

Criteria for caregivers:

* Age 18+
* Care for patient with diagnosis of NLUTD
* Care for patient who has used catheters chronically (minimum 6 months)
* Experience facilitating patients' use of intravesical Lactobacillus, gentamicin, or combination of the two

Exclusion Criteria:

* Psychiatric or psychologic conditions impacting ability to consent

About the study

The goal of this observational qualitative study is to learn about the experiences and perspectives of patients with neurogenic lower urinary tract dysfunction (NLUTD) and their caregivers regarding different types of intravesical instillations used for urinary health. The study aims to understand the perceived benefits, challenges, and opportunities related to Lactobacillus-only, gentamicin-only, and combined gentamicin-Lactobacillus instillations. The main question this study seeks to answer is:

1\. Determine patient and caregivers' preferences, and overall experiences regarding intravesical therapeutics for urinary symptoms and UTI

Researchers will compare responses from four groups: participants who have used Lactobacillus-only instillations, gentamicin-only instillations, combined gentamicin-Lactobacillus instillations, and caregivers who have experience supporting instillations.

Participants will take part in a one-hour semi-structured interview and may be contacted for brief follow-up discussions to clarify findings. Interviews will be audio-recorded, transcribed, and analyzed using qualitative data software to identify themes related to treatment preferences and acceptability.

Sponsor: Medstar Health Research Institute · Participants: 60 · Started: Jun 19, 2025

Contact the study team

Official record on ClinicalTrials.gov — NCT07390591

Locations in the U.S.

District of ColumbiaMedstar National Rehabilitation Hospital, Washington D.C.

Conditions

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.