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Sex Differences in E-Cigarette Perception

Sex Differences in E-Cigarette Perception: Study 2

Who can join

Ages 21 to 44 · All sexes · Healthy volunteers welcome

Inclusion Criteria:

* Able to read/write in English
* Current cigarette smoking
* Prior e-cigarette exposure
* Biochemically verified cigarette use
* Not trying to quit tobacco use

Exclusion Criteria:

* Significant medical concerns that would increase study risk
* Use of psychoactive drugs unless prescribed and stable
* Allergy to menthol or other e-liquid ingredients
* Dislike of menthol
* Pregnant, trying to get pregnant, breastfeeding

About the study

This study examines differences between males and females in the appeal and addiction potential of menthol flavored e-cigarettes with and without nicotine.

What is being tested

• Nicotine Level 1 (0mg/ml) (other)
• Nicotine Level 2 (36mg/ml) (other)
• Nicotine Level 3 (59mg/ml) (other)

Sponsor: Yale University · Participants: 60 · Started: Jul 30, 2026

Contact the study team

• Danielle R Davis, PhD · Phone: 2039747607

Official record on ClinicalTrials.gov — NCT07398976

Locations in the U.S.

Conditions

• Quitting Smoking (Tobacco Use Disorder)
• Vaping

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.