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Intra-aortic Balloon Counterpulsation (IABC) Compliance

Arterial Compliance as a Predictor of Clinical Outcomes With Intra-aortic Balloon Counterpulsation: A Prospective Observational Pilot Study

Who can join

Ages 18 and older · All sexes

Inclusion Criteria:

* Age ≥18 years old
* Cardiogenic shock
* Undergoing Intra-aortic Balloon Counterpulsation (IABC) as part of clinical care
* Able to provide consent or have power of attorney or next of kin provide consent

Exclusion Criteria:

* Age \<18 years old
* Unable to consent or does not have power of attorney or next of kin to consent

About the study

The investigators intend to study how baseline arterial compliance (as defined by stroke volume/pulse pressure) influences the clinical success of intraaortic balloon counterpulsation (IABC) in patients with cardiogenic shock (CS). The investigators aim to compare clinical outcomes in CS patients requiring IABC with normal compliance versus low compliance. The study will enroll patients undergoing IABC that are clinically indicated. Baseline hemodynamic measurements will be obtained and then patients would be stratified based on their compliance. Post IABC, serial hemodynamic measurements will be obtained and compared between groups. Patients will continue to be followed longitudinally until the IABC has been discontinued for any reason. The proposed study will yield results that will aid in developing a larger clinical trial and ultimately assist clinicians in determining if IABC is appropriate therapy for patients in cardiogenic shock.

Sponsor: Thomas Jefferson University · Participants: 20 · Started: Jan 27, 2026

Contact the study team

• Elizabeth R Westburg, MS · Phone: 215-955-2050
• Matthew S Delfiner, DO, MS · Phone: 215-955-2050

Official record on ClinicalTrials.gov — NCT07402018

Locations in the U.S.

Conditions

• Cardiogenic Shock

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.