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Reversal of Spinal Anesthesia Residual Motor Block Via Intrathecal Catheter

Reversal of Spinal Anesthesia Residual Motor Block Via Intrathecal Catheter: A Pilot Study

Who can join

All ages · All sexes

Inclusion Criteria:

1. Patients having elective lower extremity joint replacement surgery
2. Patients \>18 years

Exclusion Criteria:

1. Contraindications to spinal anesthesia (refusal, lumbar spinal hardware, spinal abnormalities)
2. Patient on anticoagulation not withheld
3. Patient receiving re-operation on the same joint
4. Prior intra-cranial bleeding
5. Patient's ASA status \>3
6. Non-English speaking
7. Bromage score of 6 at the time of first PACU assessment post-enrollment

About the study

The purpose of this study is to determine the feasibility of administering a predetermined amount of normal saline into the intrathecal or subarachnoid space via a small spinal catheter to reduce or eliminate the effects of previously injected spinal anesthetic following lower extremity orthopedic surgery.

What is being tested

• Normal Saline 10 mL Injection (drug)

Sponsor: Beth Israel Deaconess Medical Center · Participants: 24 · Started: Mar 19, 2026

Contact the study team

• Anna Fratello · Phone: 617-632-8058

Official record on ClinicalTrials.gov — NCT07404982

Locations in the U.S.

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.