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AI-driven Total Parenteral Nutrition Platform
Clinical Decision Support for Total Parenteral Nutrition Constituents in Neonatal Intensive Care Unit (NICU) Patients: A Pilot Study
Who can join
6 Months · All sexes
Full eligibility criteria
Inclusion Criteria: * Any newborns or infants requiring total parenteral nutrition in a neonatal ICU that performs daily laboratory tests * 6-month old at the time of admission * Any gestational age or birthweight * Any race or sex Exclusion Criteria: \- Infants deem unfit for the suggested TPN due to safety concerns by physicians
About the study
This study tests whether an artificial intelligence (AI) tool can help doctors order total parenteral nutrition (TPN) for babies in the neonatal intensive care unit (NICU). Premature babies often cannot eat by mouth and need nutrition delivered through an IV. Ordering TPN is complex, time-consuming, and mistakes can happen. This study will test an AI tool that suggests TPN formulas to doctors based on each baby's lab values and health information. Doctors can accept, change, or reject the suggestions at any time. The main goal is to measure how often doctors accept the AI suggestions. The study will also track time to complete TPN orders, weight changes, days on TPN, whether lab values stay in normal ranges, provider satisfaction, and baby health outcomes including complications such as lung disease, brain bleeding, infections, and other conditions common in premature babies. Babies admitted to the NICU who need TPN may participate if their doctors agree to use the tool. Each baby will be in the study while they need TPN, typically about 14 days. The AI tool only makes suggestions and does not replace doctor decision-making. All other care remains the same as standard practice.
What is being tested
- AI-driven total parenteral nutrition (TPN) (device)
Sponsor: Takeoff41, Inc. · Participants: 260 · Started: Jan 21, 2026
Contact the study team
- Thanaphong Phongpreecha, PhD · Phone: 551-482-4827
- Chandra Vikram, Bachelor · Phone: 317-724-2159
Official record on ClinicalTrials.gov — NCT07414576
Locations in the U.S.
| California | Stanford University, Stanford |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.