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Foregut Leaks-Role of Microbiome

The Role the Microbiome Plays in Foregut Leaks: Understanding and Utilizing This Information to Improve Patient Outcomes

Who can join

Ages 18 and older · All sexes

Inclusion Criteria:

* Patients with an esophageal or stomach leak
* Over 18 years old

Exclusion Criteria:

* Patients determined by physician/surgeon as not able to tolerate biopsy
* Under 18 years old

About the study

Aims

1. To understand the microbial composition involved with foregut leaks 2. To define the virulence changes in the microbiota following foregut leaks 3. To identify host response mechanisms and how they change with interventions 4. Utilize this information to improve patient outcomes

What is being tested

• Biopsy and fluid samples (other)

Sponsor: Baylor Research Institute · Participants: 50 · Started: Aug 14, 2020

Contact the study team

• Rehma Shabbir · Phone: 2148201722

Official record on ClinicalTrials.gov — NCT07424469

Locations in the U.S.

From ClinicalTrials.gov, data retrieved Oct 2, 2026. Each study sets its own eligibility; the study team decides who can join.