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Healthy Volunteers Enteral Nutrition Study (HEN)
Healthy Volunteers Enteral Nutrition Study
Who can join
Ages 18 to 70 · All sexes · Healthy volunteers welcome
Full eligibility criteria
Inclusion Criteria: 1. Must be able to read and understand English 2. Must be able to sign a consent form for the study Exclusion Criteria: 1. BMI \<20 or \>30 2. Unintentional weight loss of \>10% in the last 3-6 months 3. Kidney disease 4. Diagnosis of cirrhosis 5. Taking diuretics 6. Anemia - Hemoglobin \<lower limit of normal in men or \<10 g/dL in women. 7. Taking iron supplements within 2 weeks for Visit 2.1 8. Taking prebiotic or probiotic supplements or any supplement including a multivitamin within 2 weeks of Visit 2.1 9. Taking antibiotics less than 4 weeks prior to Visit 2.1 10. Diarrhea in the 2 weeks prior to Visit 2.1 11. Diabetes mellitus 12. Diagnosis of congestive heart failure 13. Diagnosis of inflammatory bowel disease or celiac disease 14. Bowel resection other than an appendectomy 15. Pregnancy or breastfeeding 16. Intolerance or allergy to nutritional formula, chicken, eggs, apples, banana, potatoes 17. Using protein supplements, including powder added to food or drinks within 2 weeks of Visit 2.1 18. Baseline bowel frequency less than every 2 days or greater than 3 times daily 19. Student or employee of any one of the investigators. 20. Anyone who cannot receive study payment (e.g. visa constraints). 21. Any condition that the investigator feels may limit the volunteer's ability to complete the study protocol.
About the study
This research study is being conducted to determine the effects of enteral nutrition on healthy people. Enteral nutrition for the purpose of this study refers to the use of a specially developed formula taken by mouth that provides all essential nutrition either in the absence of food or to supplement the intake of foods. Enteral nutrition can be used for many reasons, such as to gain or lose weight, to treat food allergies, or to reduce inflammation in certain intestinal diseases. We would like to understand the effects of enteral nutrition in the absence of intestinal inflammation.
What is being tested
- Kate Farms Peptide 1.5 (dietary supplement)
- Crohn's disease exclusion diet (other)
Sponsor: James Lewis · Participants: 25 · Started: Jun 17, 2026
Contact the study team
- Raksha Shastry, MPH · Phone: 267-896-3160
Official record on ClinicalTrials.gov — NCT07426003
Locations in the U.S.
| Pennsylvania | Penn Center for Advance Medicine, University of Pennsylvania, Philadelphia |
From ClinicalTrials.gov, data retrieved Oct 2, 2026. Each study sets its own eligibility; the study team decides who can join.