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Volume Reduction for Open Fracture Irrigation
Volume Reduction for Open Fracture Irrigation: A Randomized Prospective Feasibility Trial
Who can join
Ages 18 and older · All sexes
Full eligibility criteria
Inclusion Criteria: * Age 18 or older * Patient diagnosed with a Type I, II, or III open fracture of the appendicular skeleton by a study surgeon * For the purposes of this study, an open fracture is a fracture associated with a soft tissue wound which may or may not be contiguous with the fracture. * Open fractures of the carpals, tarsals, metacarpals, metatarsal, and/or phalanges without the involvement of a long bone or the hindfoot will not be considered. Exclusion Criteria: * Patient is unable to understand Informed Consent and/or HIPAA Authorization Form * Patient does not speak English * Patient is pregnant * Patient is unable or (in the judgment of research personnel) unlikely to attend follow-up visits. * Patient was previously enrolled in a study which has the same primary outcomes or may influence infection rate or bone healing * Patient declines to participate in study
About the study
The purpose of this study is to help doctors who treat open fractures understand how much fluid is required when cleaning out the wound. Participants will spend about 12 months in this study and will be asked to answer study questions about your recovery at your typical follow up clinic visits with your surgeon. After the surgeon has determined a participant's bone has healed, any remaining study visits can be conducted over the phone, email, and/or mail. Participants will not be asked to attend additional clinic visits as part of this study. Researchers will compare two different fluid volume protocols to determine if one results in better fracture and/or wound healing.
What is being tested
- 0.9% Sodium Chloride (drug)
Sponsor: Inova Health Care Services · Participants: 200 · Started: Mar 2, 2026
Contact the study team
- Abraham Goch, MD · Phone: (516) 209-7502
- Greg Gaski, MD · Phone: (786) 473-8895
Official record on ClinicalTrials.gov — NCT07437339
Locations in the U.S.
| Virginia | Inova Health System, Falls Church |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.