Ceribell Delirium Monitor Outcomes Pilot Study

Inclusion Criteria:

* Age is 18 years or older
* Admitted to the ICU for an expected duration ≥ 24 hours from enrollment
* Have at least one of the following conditions:

Acute Sepsis or Septic Shock Admitted to the ICU following elective cardiothoracic surgery Acute respiratory failure requiring non-invasive ventilation or high-flow nasal cannula (HFNC) oxygenation Shock requiring vasopressor therapy Mechanically ventilated - Current RASS ≥ -3 and not expected to require deep sedation (RASS \< -3) during the ICU stay

Exclusion Criteria:

\- Any structural abnormality or head condition, including the presence of a device, that would prevent the use of the Ceribell EEG system for the entire anticipated EEG monitoring period. Examples include: Craniectomy with a missing bone flap in a region where Ceribell EEG electrodes would be placed.

Anticipated use of continuous EEG for a purpose other than delirium detection during the entire expected monitoring period.

* Baseline neurological dysfunction (Glasgow Coma Scale \< 10) and pre-existing brain injuries such as stroke with known deficits, severe TBI
* History of moderate-severe dementia (IQCODE ≥ 3.5)
* APACHE II score \> 30, or SOFA \> 9 at enrollment