Home › Obesity in Children › NCT07467694
Postnatal Exercise to Activate Baby's Brown Fat
Impact of Acute Exercise and Habitual Physical Activity on Human Milk Composition and Childhood Obesity Risk
Who can join
Ages 18 to 45 · Women · Healthy volunteers welcome
Full eligibility criteria
Inclusion Criteria: * 18-45 y of age at the time of enrollment * Pre-gravid or first trimester BMI 18.5 -40 kg/m2 * Uncomplicated singleton pregnancy * Intention to exclusively breastfeed for \>3 months and, if parity \>1, that they successfully breastfed a previous pregnancy * Term pregnancy (gestational age 37 to \<42 weeks) * Infant with birth weight \>10th percentile of weight for gestational age Exclusion Criteria: * Any obstetric contra-indication to exercise at 1 month * Diagnosis of uncontrolled (HbA1c \>7%) type 1 or type 2 diabetes, or gestational diabetes managed with insulin * Intrauterine growth restriction * Pre-eclampsia or other pregnancy complications * Alcohol, cannabis or tobacco use * Known congenital metabolic, endocrine disease, or congenital illness affecting infant feeding/growth * Major fetal anomalies * Musculoskeletal issues that would make exercise difficult
About the study
The purpose of this study is to learn how exercise and physical activity during pregnancy and after pregnancy may affect the composition of breastmilk. Certain changes in breast milk after exercise may have an impact on how infants use energy. Understanding this process may improve public health recommendations for exercise during and after pregnancy. This study can help investigators learn more about how maternal exercise patterns may affect body growth and obesity risk in infants who are breastfed. This research may help identify how different factors can influence healthy weight and early development in infants.
What is being tested
- Active group (behavioral)
Sponsor: Joslin Diabetes Center · Participants: 200 · Started: Dec 1, 2025
Contact the study team
- Elvira M Isganaitis, MD, MPH · Phone: 617-309-4554
- Study Coordinator · Phone: 857-289-3455
Official record on ClinicalTrials.gov — NCT07467694
Locations in the U.S.
| Massachusetts | Joslin Diabetes Center, Boston |
| Oklahoma | Oklahoma University College of Medicine, Oklahoma City |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.