A Study to Evaluate the Impact of a Magnolia Officinalis Dietary Supplement on Immune Biomarkers in Subjects With Psoriasis

Inclusion Criteria:

* Male of female, aged 18 years or older at time of consent.
* Diagnosis of stable psoriasis affecting for at least 6 months confirmed by a dermatologist.
* Patients with psoriasis-associated comorbidities including psoriatic arthritis are permitted, as long as those comorbidities are not severe enough to require treatment with systemic therapies as defined in the exclusion criteria.
* Able to read and understand English.
* Able to read, understand, and provide informed consent.
* Able to use a personal smartphone device and download Chloe by People Science.
* Able to receive shipment of the product at an address within the United States.
* Able to adhere to study protocol (e.g., willing to collect and ship blood samples)

Exclusion Criteria:

Any potential participants who:

* Do not have a personal smartphone, internet access, or unwilling to download Chloe.
* Prior treatment with any systemic non-biologic immunosuppressive agents (e.g., methotrexate, cyclosporine, azathioprine) within 8 weeks prior to randomization.
* Prior treatment with any systemic biologic therapies (e.g., guselkumab, risankizumab, ustekinumab, secukinumab, brodalumab, infliximab, adalimumab, golimumab, etanercept) within 6 months prior to randomization
* Prior treatment with any other systemic investigational drugs within 6 months prior to randomization.
* Other Illnesses or Conditions: Participants who have the following comorbidities or gastrointestinal illnesses are excluded:
* Currently pregnant, planning to become pregnant in the next 3 months, or breastfeeding
* Any underlying medical conditions or comorbidities that may confound the assessment of digestive symptoms or the evaluation of the study outcomes.
* Have a significant illness, disease or condition which, in the opinion of the principal investigator, may impact their ability to participate in the study or impact the study outcomes.
* Known hypersensitivity or previous allergic reaction to magnolia, rice or hypromellose.
* Are unlikely for any reason to be able to comply with the trial or considered unsuited for participation in the study by the Principal Investigator.