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Prehab for Pancreatic Cancer Surgery
Multimodal Prehabilitation Prior to Pancreatic Cancer Surgery: A Pilot Study
Who can join
Ages 18 and older · All sexes
Full eligibility criteria
Inclusion Criteria: * Age ≥ 18 years * Diagnosis of pancreatic ductal adenocarcinoma (PDAC) * Planned neoadjuvant chemotherapy prior to planned surgical resection * Medically stable and cleared to participate in physical activity/exercise programming * Able to provide informed consent * Ability to read, write and understand English Exclusion Criteria: * Age \<18 years * Pregnant * Prisoner * Severe cognitive impairment that precludes informed consent or participation * Contraindications to physical activity, including unstable cardiac disease, severe pulmonary disease, or recent myocardial infarction
About the study
The goal of this clinical study is to test whether a structured prehabilitation program can be successfully used by adults with pancreatic cancer who are receiving chemotherapy before planned surgery. Prehabilitation is a program designed to improve a person's physical fitness, nutrition, and symptom control before surgery.
The study's main hypothesis is that patients with pancreatic cancer can take part in and adhere to a multimodal prehabilitation program during chemotherapy, and that doing so may improve physical function, patient experience, and early recovery after surgery.
What is being tested
- Multimodal Prehabilitation (behavioral)
Sponsor: University of Massachusetts, Worcester · Participants: 20 · Started: Mar 31, 2026
Contact the study team
- Kayla R Widdowson, MD · Phone: 774-641-1257
- James M Lindberg, MD · Phone: 508-334-5220
Official record on ClinicalTrials.gov — NCT07478185
Locations in the U.S.
| Massachusetts | UMass Memorial Medical Center, Worester |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.